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P5WD2-E Premium
According to that, it does support ATI Crossfire, so if you wanted to run 2 video cards, they would have to be ATI Crossfire equipped cards.
You can still run a single NVIDA card on the main PCI-e slot.
The regular Premium has a special set up to run any 2 PCI video cards
Universal PCI-E Slot
The Universal PCI Express technology offers utilization flexibility of the Southbridge PCI Express interface. It enables users to plug in an additional PCI Express graphics card to set up a dual graphics card platform on a single motherboard. ASUS’ own smart quick switch further detects how users installed their PCI Express devices, and intelligently reroutes the PCI Express lanes for optimized bandwidth allocation.
It's not as fast as Crossfire or SLI, but it's better than 1 card.
To run 2 NVIDA cards, you'd have to get one of these;
NVIDIA® nForce4 SLI Intel® Edition
Check out the ASUS forums and read all the reviews on Newegg before you buy. I have heard of some big driver and BIOS issues with 1 or 2 of those.
According to that, it does support ATI Crossfire, so if you wanted to run 2 video cards, they would have to be ATI Crossfire equipped cards.
You can still run a single NVIDA card on the main PCI-e slot.
The regular Premium has a special set up to run any 2 PCI video cards
Universal PCI-E Slot
The Universal PCI Express technology offers utilization flexibility of the Southbridge PCI Express interface. It enables users to plug in an additional PCI Express graphics card to set up a dual graphics card platform on a single motherboard. ASUS’ own smart quick switch further detects how users installed their PCI Express devices, and intelligently reroutes the PCI Express lanes for optimized bandwidth allocation.
It's not as fast as Crossfire or SLI, but it's better than 1 card.
To run 2 NVIDA cards, you'd have to get one of these;
NVIDIA® nForce4 SLI Intel® Edition
Check out the ASUS forums and read all the reviews on Newegg before you buy. I have heard of some big driver and BIOS issues with 1 or 2 of those.