Multi-Rail PSUs will colour code the +12V - this is typically with a Blue or black stripe down it.
You will find that the Main 24-pin and +12v connectors are on one rails and everything else is on the other one.
Moving fans off the MB fan headers will help the MB and its stability.
Ensure all 4 connectors are securely made and as suggested use a good Multi-meter to read the values of the MB, esp the +12, +5, +3.3v
Do this when posting / OS booting, OS Idle, OS Load and see what the variance is.
Use MBM5 to then correctly offset the BIOS readings to display the 'true' readings.
Check Vcore against differnet Genie % settings as some of these are not as stable.
Look in the FAQ and
also here to help you further.