Me too...I was wondering if anyone has had a similar problem to me with the Soundblaster Z.
I've had my card since release and it's been fine, up until a few months ago when I upgraded my ageing Asus motherboard and Sandybridge CPU to an AMD 3700x with a X570 motherboard.
I use the card exclusively in headphone mode without any SBX enabled.
Every now and then when I'm gaming, (4 different games so far) the sound channels get all messed up, like they drifted over to the right. Or things happening in front of me sound like they are behind me.
I'm having to open the creative control panel and switch from headphones to speakers, to headphones again to reset this behaviour.
I'm currently on the latest Sound Blaster Z drivers from the creative site.
Motherboard chipset is up to date.
No solution can been found, because of PCI-E 4.0
I just can force to use PCI-E 3.0 and change the Audio channel to 16bit, 44000Hz to delay the problem
May be we need to wait Creative to give us the latest driver to fix the problem or buy a new card
Now When I'm gaming, I change it to display audio output