I personally wouldn't opt for 3-Way SLI. The scaling generally becomes considerably worse after the second GPU. If I were you, I'd grab a single GTX285 and see how that goes. If you really need a performance boost you could pick up a second one later. Or, you could opt for a 5850 or 5870 (and possibly XFire later), since that Asus Rampage 2 supports XFire, as well. My 2 cents.