In the interest of getting a bit more out of my Mushkin RAM, I decided to change my CPU multi from 8x to 7x ... and the difference is quite noticeable.
Previously, I think the RAM clock was around 890mhz or so ... but with the 7x multiplier, running my 6400 at 3.5ghz, it's a solid 1000mhz.
Not only did it shave a second or so off of my 1meg SuperPi time ... but it is totally noticeable in certain daily functions such as windows loading and gaming.
(or maybe it's all in my head)
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(PS ... I tried running the stock timings for my RAM (4.4.3.10) at this same setting and had to clear CMOS on my P5B-lux!)