[tictoc]

Not 100% sure how Fedora handles this, but it should be as easy as pulling the 1060, adding the 5600XT, and then deleting your xorg.conf. This assumes that you are running xorg and not wayland.

Unless Fedora is doing some whacky things you shouldn't really even need to remove the drivers. I would remove the nvidia drivers after adding the 5600XT, but I've had systems with mixed AMD NVIDIA cards, swapped cards, and every imaginable combination.

I'm not sure how Fedora packages Mesa, but outside of a few select scenarios Mesa's vulkan is better than amdvlk (AMDs standalone vulkan implementation).

I have been on Arch for many years, so unforunately I can't say for sure if it will be as simple on Fedora as it is on Arch.

 

[jakethesnake438]

Navi 10 drivers are baked in to the kernel since ~5.3
Should be plug and play

AMD Navi 10 [Radeon RX 5600 OEM/5600 XT / 5700/5700 XT]

A database of all the hardware that works under linux

linux-hardware.org

 

[rdr09]

I've tried my 5700XT on Ubuntu and MacOS (Catalina/Ryzentosh) and it worked.

 

[Paradigm Shifter]

As others have said, if not using the proprietary drivers it should be as easy as a direct swap. If Xorg has any custom config files they may need to be removed/regenerated. Any newer kernel will have pretty good support for AMD cards now.