Anyway, I searched on USPTO and found one way of how these things are done:
http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2 FPTO%2Fsearch-bool.html&r=50&f=G&l=50&co1=AND&d=PG01&s1=%22cryog enic+cooler%22&OS="cryogenic+cooler"&RS="cryogenic +cooler"
True, but then again, they could easily make a larger one if they feel like it I would assume. The bottom may be large but it is not as demanding as a good single stage of that size.
Actually, cascade TEC's are horribly inefficient compared to a single stage of the same power/deltaT. Each peltier adds it's own heat in conjunction to the heat of the other, in addition to the heat load that you're trying to cool. The only thing I'm not sure of is the new thin film peltiers, because I'm not sure of their efficiency. They're not in production yet, though.
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