As spotted by patent sleuth @Underfox3, AMD has field a patent what appears to be a means of using a big.LITTLE-esque hybrid computing architecture that comes with a mixture of high-performance cores and smaller low-performance cores. As with all patent filings, this doesn't assure that AMD will bring this type of device to market, but it certainly shows the company is busy researching hybrid architectures
The patent outlines a new instruction set subset implementation for low power operation. AMD's implementation allows for one subset of instructions to execute on larger full-featured processing cores optimized for higher performance, while a second subset of instruction run on smaller simplified cores designed for power efficiency. AMD's patent outlines a method whereby the cores use a shared memory location to enable threads to move between the two types of cores based upon certain variables.