Vundo on Vista-64bit

Mcafee recently popped up having detected Vundo. I remember this trojan because it infected a friends comp a while back. I remember it being a pain in the ass for him to get rid of.

So in response to the detection, I researched what Vundo is and some of the symptoms that are caused by Vundo...and realized I've had it for a lot longer than I thought.

My computer randomly crashes making me do a manual restart, random pop-ups will appear that have been identified as more Vundo crap. My Harddrive space will fluctuate dramatically.

I am running Vista 64bit

So my question is: Does anyone know of a permanent way to get rid of Vundo?

I downloaded Malwarebyte's Anti-Malware and initiated a scan, it came up with 13 items and I immediately quarantined and deleted them but I still have Vundo on my computer.

I would try a system restore but I have no idea how far back I've had it, as Mcafee has only now just detected it, despite the symptoms being there a long time.

I appreciate the help and thank you