Write cache buffers increase the odds of data loss when you suffer a power failure, but you gain increased performance in exchange, because a small number of writes can be buffered and completed instantly, even though they haven't actually been written to disk.
Turning off write caching forces the drive to do what it's told, before the program proceeds. This can make games laggy, as they often record everything that is happening to log files, in case they crash. While the drive navigates to the right spot, you would have ~15ms where it can't read files (textures/models) or do anything else. If you happen to need a new texture on that frame, then the frame takes a lot longer to finish rendering, so your framerate suffers.
Note: Not all games write lots of stuff, so not all games are affected. But you should turn it on, unless you have constant power failures or BSODs.
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