In my opinion, S1220A is garbage.
There's poor driver support from Realtek and Asus, and for me, on a Strix B450-F Gaming motherboard, I experienced random audio crashes with the latest drivers, that were not truly fixed despite trawling the internet for, and testing, older drivers. Other examples include Sonic Studio randomly resetting the chip functionality where it had to be reselected as the default despite no prior changes in audio use.
Not to mention the hum coming from my speakers which were fixed by using a ground loop isolator (yes it's true that interference causing hums in sound can come from other causes than audio, such as the myriad of cables plugged into the back of a PC (shielding and so on)).
But in the end, I disabled the onboard S1220A sound and bought a Soundblaster AE-5.
All my issues disappeared instantly.
At defaults, the sound was clearer, heavier and more substantial. There are also far more options than the crappy Sonic Studio.
And the ground loop hum, through the same speakers, was unmistakably lower when driven by the AE-5 compared with the S1220A. I still use the isolator (which eliminates that hum 100%), but the sound quality improvements and driver reliability, ontop of the reduced ground loop hum, over the S1220 is significant, and thus why I can't recommend it at all.
I did research Xonar cards before buying the AE-5. However, they appear to have a worse record of drivers and performance, based upon reading many reviews and so on.
As things are at the moment, my AE-5 performs fantastically well, and i'd recommend it for that reason alone (I don't use the gimmicky Creative bloatware like scout radar, though).
So I can't recommend the S1220A to anyone on the basis of my experiences.